By Christopher R. Jacobs, Daniel J. Kelly (auth.), Paulo R. Fernandes, Paulo Jorge Bártolo (eds.)
This publication offers a suite of chapters describing the state-of-the-art on computational modelling and fabrication in tissue engineering.
Tissue Engineering is a multidisciplinary box related to scientists from varied fields. the advance of mathematical tools is sort of correct to appreciate telephone biology and human tissues to boot to version, layout and fabricate optimized and shrewdpermanent scaffolds.
The bankruptcy authors are the prestigious keynote audio system on the first Eccomas thematic convention on Tissue Engineering the place the emphasis used to be on mathematical and computational modeling for scaffold layout and fabrication. this actual region of tissue engineering, whose objective is to procure substitutes for challenging tissues corresponding to bone and cartilage, is growing to be in significance.
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Extra info for Advances on Modeling in Tissue Engineering
21. Martin RB, Burr DB, Sharkey NA (1998) Skeletal Tissue Mechanics. Springer-Verlag, NY. 22. Svanberg K (1987) The method of moving asymptotes – a new method for structural optimisation. Int J Numer Methods Eng 24:359-373. Multiscale Modelling of Bone Tissue 33 23. Fleury C (1989) CONLIN: an efficient dual optimizer based on convex approximation concepts. Struct Optim 1:81-89. 24. Coelho PG, Fernandes PR, Guedes JM, Rodrigues HC, 2008. A hierarchical model for concurrent material and topology optimization of three-dimensional structures.
Biomech. 42:830-837. 17. Lucchinetti E (2001) Composite Model of Bone Properties. In: Cowin SC (ed) Bone Mechanics Handbook, 2nd Edition, CRC Press. 18. Guedes J, Kikuchi N, (1990) Preprocessing and postprocessing for materials based on the homogenisation method with adaptive finite element method. Comput Meth Appl Mech Eng 83:143-198. 19. Rodrigues H, Guedes J, Bendsøe M (2002) Hierarchical optimisation of material and structure. Int J Struct Multidisc Optim 24:1-10. 20. Bendsøe MP, Sigmund O, (2003) Topology optimization theory, methods and applications.
If the material is linear elastic, effective nonlinear elasticity can only be created through microstructure geometric nonlinearities including contact and buckling within the porous microstructure. If the base material is nonlinear elastic, of course, effective nonlinear elastic behavior can be created through any design. We further demonstrated that recently developed bioresorbable elastomers (POC, PGS, and PGD) demonstrate both base nonlinear elastic behavior and designed effective nonlinear elastic behavior.
Advances on Modeling in Tissue Engineering by Christopher R. Jacobs, Daniel J. Kelly (auth.), Paulo R. Fernandes, Paulo Jorge Bártolo (eds.)